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Li-Chon-Luh and R. (4) As mature osteoclasts resorb bone, matrix-bound factors such as TGF- insulin-like growth factor 1 (IGF-1), other growth factors, and cytokines are released.

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6 atm (Example 14-4) (Example 14-7) (Example 14-9) (Example 14-13) The first of these is so small that it would be hard to measure precisely.B.

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2 A Multitude of Simple Interfaces. R1 CHO, R2 H, R3 OH: methyl (3aR,4R,5S,5aR, 10bR,13aR)-3a-ethyl-9-[(5S,7R,9S)-5-ethyl-5-hydroxy- 9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H- 3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-6- formyl-4,5-dihydroxy-8-methoxy-3a,4,5,5a,6,11,12,13a- octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate (deacetylvincristine), Methyl (5S,7R,9S)-9-[(3aR,4R,5S,5aR,10bR,13aR)-5-carbamoyl- 3a-ethyl-4,5-dihydroxy-8-methoxy-6-methyl-3a,4,5,5a,6,11,12,13a- octahydro-1H-indolizino[8,1-cd]carbazol-9-yl]-5-ethyl-5-hydroxy- 1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino- [4,5-b]indole-9-carboxylate sulfate.

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471For a discussion of selectivity, see Spino, C.

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